What is the Difference Between Anaphase and Telophase?

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The difference between anaphase and telophase lies in the process and outcomes of these two stages of mitosis. Here is a comparison of the two stages:

Anaphase:

  • Occurs after metaphase
  • Cohesin proteins binding the sister chromatids together break down
  • Sister chromatids (now called chromosomes) pull toward opposite poles
  • Non-kinetochore spindle fibers lengthen, elongating the cell

Telophase:

  • Occurs after anaphase
  • Chromosomes arrive at opposite poles and begin to condense
  • Nuclear envelope material surrounds each set of chromosomes
  • The mitotic spindle breaks down

In summary, during anaphase, the sister chromatids separate and move towards opposite ends of the cell, while in telophase, the chromosomes arrive at opposite poles, and nuclear envelope material surrounds each set of chromosomes.

Comparative Table: Anaphase vs Telophase

Here is a table comparing the differences between anaphase and telophase:

Feature Anaphase Telophase
Chromosome arrangement Sister chromatids separate and move towards opposite ends of the cell Daughter chromosomes reach maximum condensation level
Microtubules Microtubules shorten, pulling sister chromatids apart Microtubules disassemble, spindle fibers disappear
Nuclear membrane Nuclear membrane breaks down Nuclear membrane reforms around separated chromosomes
Nucleoli Nucleoli disappear Nucleoli reappear
Spindle checkpoint Spindle checkpoint ensures proper alignment of chromosomes Spindle checkpoint not present
Cell shape Cell elongates as chromosomes move towards opposite poles Cell returns to a more rounded shape
Cytokinesis Overlaps with anaphase, begins after spindle checkpoint Overlaps with telophase, completes cell division

In anaphase, the sister chromatids separate and move towards opposite ends of the cell, while microtubules shorten and pull the chromosomes apart. The nuclear membrane breaks down, and the cell elongates as the chromosomes move. In telophase, the daughter chromosomes reach their maximum condensation level, microtubules disassemble, and the nuclear membrane reforms around the separated chromosomes. The nucleoli reappear, and the cell returns to a more rounded shape.