What is the Difference Between Autosomal and X-Linked Pedigree?
🆚 Go to Comparative Table 🆚The main difference between autosomal and X-linked pedigrees lies in the inheritance patterns and the distribution of affected individuals in the pedigree. Here are the key distinctions between the two:
- Affected Individuals: In autosomal pedigrees, both males and females are equally likely to be affected, usually in equal proportions. In X-linked pedigrees, males are much more commonly affected than females.
- Carriers: In autosomal pedigrees, both male and female individuals can be carriers. In X-linked pedigrees, carriers are always female individuals, never male.
- Inheritance Patterns: Autosomal traits generally appear to affect individuals in every generation, while X-linked traits show 'crisscross inheritance'.
To determine if a pedigree chart shows an autosomal or X-linked disorder, you can:
- Observe the distribution of affected individuals in the pedigree. If most of the males are affected, then the disorder is likely X-linked.
- Look for carriers. If female individuals are the carriers, then the disorder is likely X-linked.
- Appearance in Generations: Autosomal traits tend to appear in every generation, while X-linked traits may skip generations.
In summary, autosomal pedigrees show equal distribution of affected individuals between males and females, while X-linked pedigrees show a predominance of affected males. Additionally, autosomal traits tend to appear in every generation, while X-linked traits may skip generations.
Comparative Table: Autosomal vs X-Linked Pedigree
The main difference between autosomal and X-linked pedigree lies in the type of chromosomes involved in the inheritance of traits. Autosomal pedigree describes the inheritance of traits of the genes in autosomes, while X-linked pedigree describes the inheritance of traits of the genes in sex chromosomes. Here is a table illustrating the differences between autosomal and X-linked pedigree:
Feature | Autosomal Pedigree | X-Linked Pedigree |
---|---|---|
Chromosomes | Autosomes (non-sex chromosomes) | Sex chromosomes (X-chromosome) |
Inheritance Pattern | Mendelian inheritance pattern | Criss-cross inheritance pattern |
Male-to-Male Transmission | Observed | Not observed |
Affected Males vs. Females | Both males and females are equally likely to be affected (usually in equal proportions) | Males are much more commonly affected than females |
In autosomal pedigree, both males and females have an equal chance of inheriting and being affected by the trait. On the other hand, in X-linked pedigree, males are more commonly affected by the trait due to the inheritance pattern through the X chromosome.
- Sex-linked vs Autosomal
- X linked vs Y linked Inheritance
- Punnett Square vs Pedigree
- Autosomal Dominant vs Autosomal Recessive Disorders
- X Linked Dominant vs X Linked Recessive
- Pedigree vs Karyotype
- Autosomes vs Sex Chromosomes
- X vs Y Chromosomes
- Autosomes vs Allosomes
- Mendelian vs Chromosomal Disorders
- Genetics vs Heredity
- Autosomes vs Chromosomes
- Mendelian vs Non Mendelian Inheritance
- Heredity vs Hereditary
- XX vs XY Chromosomes
- Autosomal Dominant vs Recessive Polycystic Kidney Disease
- Monogenic vs Polygenic Inheritance
- Monogenic Disorders vs Chromosomal Disorders
- Maternal vs Paternal