What is the Difference Between Dicyclomine and Diclofenac?
🆚 Go to Comparative Table 🆚The main difference between dicyclomine and diclofenac lies in their uses and mechanisms of action.
Dicyclomine is an anticholinergic drug used to treat spasms of the intestines, such as those associated with irritable bowel syndrome. It works by relaxing the muscles in the stomach and gut, thereby relieving cramps and pain. Some common side effects of dicyclomine include dry mouth, blurry vision, weakness, sleepiness, and lightheadedness.
On the other hand, diclofenac is a nonsteroidal anti-inflammatory drug (NSAID) used to treat pain and inflammatory diseases, including gout. It works by reducing inflammation and pain signaling in the body. Common side effects of diclofenac include gastrointestinal issues, such as stomach pain, nausea, and diarrhea.
In some cases, dicyclomine and diclofenac are combined to relieve abdominal pain and cramps. This combination is primarily used to treat irritable bowel syndrome (IBS) and abdominal cramps occurring due to dysmenorrhea (painful periods).
Comparative Table: Dicyclomine vs Diclofenac
Here is a table comparing the differences between dicyclomine and diclofenac:
Dicyclomine | Diclofenac |
---|---|
Anticholinergic drug | NSAID (nonsteroidal anti-inflammatory drug) |
Treats spasms of the intestines, e.g., irritable bowel syndrome | Treats pain and inflammatory diseases, including gout |
Oral administration | Can be administered in various forms, such as oral tablets, intramuscular injections, and topical gels |
Protein binding ability of about 99% | Inhibits cyclooxygenase (COX)-1 and-2, enzymes responsible for producing prostaglandins that contribute to inflammation and pain signaling |
Elimination half-life of around 5 hours | Used as first-line therapy for acute and chronic pain and inflammation |
Side effects include dry mouth, blurry vision, weakness, sleepiness, and lightheadedness | Brand names include Aleve Arthritis Pain, Arthrotec, Cambia, Cataflam, Flector, Licart, Lofena, Pennsaid, Previdol, Solaraze, Voltaren, Voltaren Emulgel, Xrylix, Zipsor, and Zorvolex |
Please note that this table is not exhaustive and only highlights some key differences between the two medications. Always consult a healthcare professional for more information on these medications and their uses.
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