What is the Difference Between Lambda Phage and M13 Phage?
🆚 Go to Comparative Table 🆚Lambda phage and M13 phage are two types of bacteriophages that infect bacterial cells, specifically Escherichia coli (E. coli). They are both used as cloning vectors in genetic engineering. The main differences between lambda phage and M13 phage are:
- Structure: Lambda phage is a head to tailed bacteriophage with a linear double-stranded genome. In contrast, M13 phage is a filamentous bacteriophage with a single-stranded circular genome.
- Genome Size: The size of the lambda phage genome is about 48 kb, while the size of the M13 phage genome is about 6.4 kb.
- Family: Lambda phage belongs to the family Siphoviridae, while M13 phage belongs to the family Inoviridae.
- Life Cycle: Lambda phage is a temperate phage that undergoes both lytic and lysogenic cycles. On the other hand, M13 phage releases without killing the bacterial cell.
In summary, lambda phage and M13 phage are two types of bacteriophages that infect E. coli and are used as cloning vectors in genetic engineering. They differ in their structure, genome size, family, and life cycle.
On this pageWhat is the Difference Between Lambda Phage and M13 Phage? Comparative Table: Lambda Phage vs M13 Phage
Comparative Table: Lambda Phage vs M13 Phage
Here is a table comparing the differences between Lambda Phage and M13 Phage:
Feature | Lambda Phage | M13 Phage |
---|---|---|
Family | Siphoviridae | Inoviridae |
Genome Type | Double-stranded linear DNA | Single-stranded circular DNA |
Genome Size | 48.5 kbp | 6.4 kbp |
Life Cycle | Temperate phage, undergoes both lytic and lysogenic cycles | Releases without killing the bacterial cell |
Infection | Head-to-tailed bacteriophage | Filamentous bacteriophage |
DNA Insert Size | 12 kb | 12 kb |
Cloning Vector | Widely used | One of the first vectors developed for molecular cloning |
Lambda Phage and M13 Phage are both bacteriophages that infect E. coli and are widely used as cloning vectors in genetic engineering.
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- Retrovirus vs Bacteriophage
- Lytic vs Lysogenic
- Bacteriophage vs TMV
- Prophage vs Provirus
- Virulent vs Temperate Phage
- Microphage vs Macrophage
- T2 vs T4 Bacteriophage
- Obligate Intracellular Parasite vs Bacteriophage
- Genomic vs Plasmid DNA
- Kappa vs Lambda Light Chains
- Phosphorylase vs Phosphatase
- Plasmid vs Transposon
- Phagolysosome vs Phagosome
- Plasmid vs Episome
- Ligase vs Lyase