What is the Difference Between Lipoprotein and Apolipoprotein?
🆚 Go to Comparative Table 🆚Lipoproteins and apolipoproteins are both involved in the transport and distribution of triglycerides and cholesterol in the body. However, they have distinct roles and characteristics:
Lipoproteins:
- Complex, water-soluble macromolecules composed of a hydrophobic lipid component and one or more specific apolipoproteins.
- There are five main types of lipoproteins, including HDL (good cholesterol) and LDL (bad cholesterol).
- Lipoproteins carry cholesterol and triglycerides to cells in the body.
Apolipoproteins:
- Protein molecules that form complexes with lipids to form lipoproteins.
- Specific to each type of lipoprotein.
- Have structural, enzymatic, and receptor-binding roles.
In summary, lipoproteins are the complex particles that transport lipids, while apolipoproteins are the proteins that form these complexes. Both are essential for fat and cholesterol metabolism and act as biomarkers for various cardiovascular states and metabolic imbalances.
Comparative Table: Lipoprotein vs Apolipoprotein
Lipoproteins and apolipoproteins are both involved in the transport and metabolism of lipids in the blood. Here is a table comparing the differences between them:
Lipoproteins | Apolipoproteins |
---|---|
Lipo- means "fat" and proteins are the protein components of lipoproteins | Apolipo- means "fat" and proteins are the protein components of lipoproteins |
Carriers of lipids in the blood | Protein components of lipoproteins |
Examples: Low-density lipoprotein (LDL), High-density lipoprotein (HDL), VLDL (very-low-density lipoprotein) | Examples: Apolipoprotein B (apoB), Apolipoprotein A-I (apoA-I) |
LDL-C is the cholesterol carried by LDL particles | Apolipoprotein B-100 is carried on all proatherogenic lipoproteins in a 1:1 ratio |
Lipoproteins are complex particles composed of proteins, cholesterol, triglycerides, and phospholipids. They transport lipids throughout the body, with different lipoproteins carrying specific types of lipids. Apolipoproteins are the protein components of lipoproteins and play a crucial role in lipid transport and receptor binding.
Apolipoprotein B (apoB) is a major protein component of non-HDL particles, such as LDL, VLDL, and intermediate-density lipoprotein (IDL), while apolipoprotein A-I (apoA-I) is a major protein component of HDL particles. Levels of apoB and apoA-I have been suggested to be better predictors of cardiovascular risk than traditional lipid measurements, such as LDL-C and HDL-C.
- HDL And LDL
- HDL vs LDL Cholesterol
- Lipoprotein Lipase vs Hormone Sensitive Lipase
- LDL vs VLDL Cholesterol
- Hyperlipidemia vs Hypercholesterolemia
- Chylomicrons vs VLDL
- Non-HDL Cholesterol vs LDL Cholesterol
- Dyslipidemia vs Hyperlipidemia
- Hypercholesterolemia vs Dyslipidemia
- Lipids vs Fats
- Glycolipids vs Phospholipids
- Lipid Profile vs Liver Function Test
- Triglycerides vs Phospholipids
- Fat vs Cholesterol
- Cholesterol vs Triglycerides
- Lipolysis vs Lipogenesis
- Liposome vs Micelle
- Simple vs Complex Lipids
- Lipophilic vs Hydrophilic