What is the Difference Between Multifocal and Multicentric Breast Cancer?
🆚 Go to Comparative Table 🆚The main difference between multifocal and multicentric breast cancer lies in the location and spread of the tumors within the breast.
- Multifocal breast cancer: This is defined as having more than one distinct tumor within the same quadrant of the breast. In other words, multiple tumors are found in the same area of the breast, but they are separate and distinct from one another.
- Multicentric breast cancer: This is defined as having multiple distinct tumor foci found in different quadrants of the breast. In this case, the tumors are located in different areas of the breast, indicating a more widespread presence of the cancer.
Both multifocal and multicentric breast cancers are considered more extensive than unifocal breast cancer, which involves a single tumor within the breast. The surgical approach and treatment plans for these types of breast cancer may differ, with multifocal and multicentric breast cancers more frequently treated with mastectomy rather than breast-conserving surgery. However, the prognosis for patients with multifocal or multicentric breast cancer does not differ significantly from those with unifocal breast cancer, provided they receive appropriate treatment.
Comparative Table: Multifocal vs Multicentric Breast Cancer
Here is a table comparing multifocal and multicentric breast cancer:
Feature | Multifocal Breast Cancer | Multicentric Breast Cancer |
---|---|---|
Definition | More than one distinct tumor within the same quadrant of the breast. | Distinct tumor foci found in different quadrants of the breast. |
Surgical Treatment | More frequently treated with mastectomy (81.2%) than with breast-conserving surgery (18.9%). | Breast conserving surgery has traditionally been considered a contraindication due to concerns about recurrence and tumor multifocality. |
Adjuvant Therapy | Patients with multifocal and multicentric cancers more frequently received chemotherapy. | The presence of multifocal and multicentric disease is associated with poor prognostic factors. |
Prognosis | No significant association between tumor multifocality and disease-free survival has been found in some studies. | The evidence supporting the practice of breast conserving surgery in selected cases is limited. |
Please note that the treatment and prognosis for multifocal and multicentric breast cancer can vary depending on individual cases and the specific characteristics of the tumors. It is essential to consult with a healthcare professional for personalized advice on diagnosis and treatment options.
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