What is the Difference Between Myeloblast and Lymphoblast?

Myeloblasts and lymphoblasts are two distinct types of immature blood cells that play crucial roles in our immune system. They have different characteristics and functions, as well as differences in their formation, size, shape, and size of the nucleus, nuclear chromatin, number of nucleoli, cytoplasm, and what they are differentiated into. Here are the key differences between myeloblasts and lymphoblasts:

1. Formation: Myeloblasts are immature white blood cells formed in the bone marrow, while lymphoblasts are immature cells that develop into lymphocytes upon maturity.
2. Size: Myeloblasts are larger, with a size of approximately 15-20µm, compared to lymphoblasts, which are smaller, with a size of 10-18µm.
3. Shape of Nucleus: The nucleus of myeloblasts is curved and could be S, V, or C shaped, while the nucleus of lymphoblasts is round.
4. Nuclear Chromatin: Myeloblasts have fine meshwork nuclear chromatin, while lymphoblasts have somewhat clumped nuclear chromatin.
5. Number of Nucleoli: Myeloblasts have two to five nucleoli, while lymphoblasts have one to two nucleoli.
6. Cytoplasm: Myeloblasts have a blue, scanty, and agranular cytoplasm, while lymphoblasts have an even scantier cytoplasm compared to myeloblasts, which is agranular and blue in appearance.
7. Differentiation: Myeloblasts give rise to granulocytes, such as neutrophils, eosinophils, and basophils, while lymphoblasts develop into lymphocytes, such as B and T lymphocytes.

In summary, myeloblasts and lymphoblasts are distinct immature blood cells with different sizes, shapes, and functions. Myeloblasts develop into granulocytes, while lymphoblasts mature into lymphocytes.

Comparative Table: Myeloblast vs Lymphoblast

The main differences between myeloblasts and lymphoblasts are summarized in the table below:

Myeloblasts and lymphoblasts are two types of progenitor cells that originate from the hemocytoblast, a multipotent stem cell that can differentiate into various types of blood cells. Myeloblasts develop into granulocytes, while lymphoblasts develop into lymphocytes.