What is the Difference Between Quinine and Hydroxyquinoline?

Quinine and hydroxyquinoline are both organic compounds, but they have different structures and properties. Here are the main differences between the two:

1. Origin: Quinine is a naturally occurring compound found in cinchona bark, while hydroxyquinoline is a derivative of quinine and a less commonly studied organic compound.
2. Chemical Structure: Quinine has the chemical formula C20H24N2O2, and its IUPAC name is (8α,9R)-6'-Methoxycinchonan-9-ol. Hydroxyquinoline, on the other hand, is a derivative of quinine and has a different chemical structure.
3. Medicinal Properties: Quinine has been used as a drug to treat malaria, and its medicinal properties include antimalarial, anticancer, and antioxidant activities. Hydroxyquinoline and its derivatives hold medicinal properties such as antineurodegenerative, anticancer, antioxidant, antimicrobial, anti-inflammatory, and antidiabetic activities.
4. Chelating Properties: 8-Hydroxyquinoline, a specific hydroxyquinoline derivative, is known for its metal chelating properties and has been used in various medicinal applications.

In summary, quinine and hydroxyquinoline are both organic compounds with different chemical structures, origins, and medicinal properties. Quinine is a naturally occurring compound found in cinchona bark and has been used as a drug to treat malaria, while hydroxyquinoline is a derivative of quinine with various medicinal applications and chelating properties.

Comparative Table: Quinine vs Hydroxyquinoline

The main difference between quinine and hydroxyquinoline is their structure and medicinal applications. Here is a comparison table highlighting the differences:

Quinine is a medication used to treat malaria and babesiosis, while hydroxyquinoline is a derivative of quinoline with a hydroxyl group attached to one of the carbons. Hydroxyquinoline and its derivatives have a wide range of medicinal properties, making them potential candidates for various therapeutic applications.