What is the Difference Between Metabolic and Respiratory Acidosis?
🆚 Go to Comparative Table 🆚Metabolic and respiratory acidosis are two distinct types of acidosis that arise from different causes. Here are the key differences between the two:
Metabolic Acidosis:
- Occurs when the body produces too much acid or the kidneys fail to remove enough acid from the blood.
- Characterized by an increase in the hydrogen ion concentration in the body.
- Can be caused by various factors, including untreated diabetes, kidney disease, kidney failure, loss of bicarbonate, and blood poisoning.
- Symptoms may include an accelerated heartbeat, confusion, and fatigue.
- Diagnosed through blood and urine tests.
- Treatment may involve sodium bicarbonate, intravenous fluids, and insulin.
Respiratory Acidosis:
- Occurs when the lungs cannot remove excess carbon dioxide from the body, making the blood more acidic.
- Results from decreased ventilation, leading to a buildup of carbon dioxide in the blood.
- Causes include breathing problems, conditions affecting the nerves or muscles in the chest, asthma, brain injuries, and excessive or disordered substance use.
- Symptoms may include anxiety, fatigue, and memory loss.
- Diagnosed through a physical exam and testing.
- Treatment involves addressing the underlying cause, such as improving lung function or treating the condition affecting the nerves or muscles in the chest.
In summary, metabolic acidosis is caused by an accumulation of acids in the body due to overproduction or impaired excretion, while respiratory acidosis results from inadequate removal of carbon dioxide from the lungs. The symptoms, diagnosis, and treatment methods for each type of acidosis differ accordingly.
Comparative Table: Metabolic vs Respiratory Acidosis
Here is a table comparing the differences between metabolic and respiratory acidosis:
Feature | Metabolic Acidosis | Respiratory Acidosis |
---|---|---|
Cause | Excessive acid production or bicarbonate loss in the blood | Inadequate excretion of carbon dioxide through the lungs |
pH | Decreased (<7.35) | Decreased (<7.35) |
PaCO2 | Normal or slightly decreased | Increased |
HCO3- | Decreased | ordinarily compensated by the kidneys |
Common Causes | Kidney disease, diabetic ketoacidosis | Asthma, COPD, heart failure, anesthesia, medications such as opioids and sedatives |
Compensation | Kidneys increase bicarbonate conservation and secretion of H+ to reestablish proper pH | Respiratory system increases respiratory rate to excrete CO2, but compensation is less efficient |
Both metabolic and respiratory acidosis result in a decrease in blood pH, but they have different causes and compensation mechanisms. Metabolic acidosis is typically caused by kidney disease or certain medical disorders, while respiratory acidosis is often caused by conditions that affect the lungs' ability to excrete carbon dioxide.
- Metabolic Acidosis vs Metabolic Alkalosis
- Acute vs Chronic Respiratory Acidosis
- Alkalosis vs Acidosis
- Ketoacidosis vs Lactic Acidosis
- Ketosis vs Ketoacidosis
- Acidosis vs Acidemia
- Aerobic Respiration vs Anaerobic Respiration
- Fermentation vs Respiration
- Aerobic vs Anaerobic Metabolism
- Ventilation vs Respiration
- Respiration vs Cellular Respiration
- Fermentation vs Anaerobic Respiration
- Diabetes Mellitus vs Diabetic Ketoacidosis
- Hyperventilation vs Hypoventilation
- Breathing vs Respiration
- Breathing vs Cellular Respiration
- Circulatory vs Respiratory System
- Carbonic Acid vs Bicarbonate
- Diabetic Ketoacidosis vs Starvation Ketoacidosis